Wednesday 30 November 2011

Laboratory Synthesis Of N-Acetylcysteine


N-Acetylcysteine ChemicalName (IUPAC): N- acetyl- L- cysteine
N-AcetylcysteineUse: mucolytic agent
N-Acetylcysteine MW: 163.20
N-AcetylcysteineMF: C5H9NO3S
N-Acetylcysteine LD50: 400 mg/kg (M, i.p.); 3800 mg/kg (M, i.v.); 7888 mg/kg (M, p.o.);
1140 mg/kg (R, i.v.); 5050 mg/kg (R, p.o.);
700 mg/kg (dog, i.p.); 700 mg/kg (dog, i.v.); >1 g/kg (dog, p.o.)
N-Acetylcysteine Reference(s):
  1. US 3 091 569 (Mead Johnson;. 28.5.1963; appl. 26.8.1960).
  2. US 3 184 505 (Mead Johnson; 18.5.1965; appl. 18.6.1962).
  3. Smith, H.A.; Gorin, G.: J. Org. Chem. (JOCEAH) 26, 820 (1961).
  4. ammonium salt (mucolysis of bronchial mucus by nebulization):DOS 2 305 271 (Bristol-Myers; appl. 2.2.1973; USA-prior. 3.2.1972).
tags-synthesis of drugs,method of preparation of N-Acetylcysteine ,molecular weight N-Acetylcysteine  , molecular formula of  N-Acetylcysteine,structure of N-Acetylcysteine

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