Monday, 28 November 2011

Laboratory Synthesis Of alpha Acetyl Digoxin

alpha Acetyl Digoxin MW: 822.99
alpha Acetyl DigoxinMF: C43H66O15
alpha Acetyl Digoxin Use: cardiotonic, cardiac glycoside
alpha Acetyl Digoxin LD50: 3300 mg/kg (g. p., p.o.);200 mg/kg (cat, p.o.)
Reference(s):
a Fieser, L.F.; Fieser, M.: Steroide, p. 801, Verlag Chemie, Weinheim 1961.
b GB 1 162 614 (Heilmittelwerke Wien; appl. 1.2.1968; A-prior. 7.2.1967).
Gisvold, O.: J. Pharm. Sci. (JPMSAE) 61, 1320 (1972).
Alternative syntheses:
DE 2 010 422 (Boehringer Ing.; appl. 5.3.1970). (Acetyldigitoxin, q. v.).
Rietbrock, N.; Kuhlmann, J.: Naunyn-Schmiedeberg's Arch. Pharmacol. (NSAPCC) 279,
413 (1973).
Formulation(s):
sol. 0.5 mg/ml; tabl. 0.25 mg, 0.2 mg

tags-synthesis of drugs,method of preparation of Acetyl Digoxin,molecular weight Acetyl Digoxin  , molecular formula of   Acetyl Digoxin,structure of Acetyl Digoxin

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