Laboratory Synthesis Of Amlodipine

Amlodipine IUPAC Chemical Name: 2- [(2- amino ethoxy )methyl]- 4- (2- chloro phenyl)- 1 ,4- di hydro- 6- methyl- 3 ,5- pyridine dicarboxylic acid 3- ethyl 5- methyl ester
Amlodipine Use: calcium antagonist, antianginal,antihypertensive
Amlodipine MW: 408.88
Amlodipine MF: C20H25ClN2O5
Reference(s):
EP 89 167 (Pfizer; appl. 8.3.1983; GB-prior. 11.3.1982).
besylate salt:
EP 244 944 (Pfizer; appl. 31.3.1987; GB-prior. 4.4.1986).
racemate resolution:
EP 331 315 (Pfizer; appl. 16.2.1989; GB-prior. 27.2.1988).
Arrowsmith, J.E. et al.: J. Med. Chem. (JMCMAR) 29, 1696 (1986).

tags-synthesis of drugs,method of preparation of Amlodipine ,molecular weight Amlodipine  , molecular formula of Amlodipine,structure of Amlodipine