Laboratory Synthesis Of Amodiaquine

Amodiaquine IUPAC Chemical Name: 4- [(7- chloro- 4- quinolinyl )amino]- 2- [(di ethyl amino )methyl ]phenol
Amodiaquine Use: antimalarial
Amodiaquine MW: 355.87
Amodiaquine MF: C20H22ClN3O
Amodiaquine LD50: 550 mg/kg (M, p.o.)
Reference(s):
US 2 474 821 (Parke Davis; 1949; prior. 1945).
Burckhalter, J.F. et al.: J. Am. Chem. Soc. (JACSAT) 68, 1894 (1946).

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