Laboratory Synthesis Of Atorvastatin calcium

Atorvastatin calcium IUPAC Chemical Name: [R- (R *,R *)]-2- (4- fluoro phenyl)- b ,d- di hydroxy- 5- (1- methyl ethyl)
- 3- phenyl- 4- [(phenylamino )carbonyl]- 1 H- pyrrole- 1- heptanoic acid calcium salt (2 :1 )
Atorvastatin calcium Use: hyperlipidemic, HMG-CoA-reductase inhibitor
Atorvastatin calcium MW: 1155.36
Atorvastatin calcium MF: C66H68CaF2N4O10
Atorvastatin calcium Reference(s):
a ,b US 4 681 893 (Warner-Lambert; appl. 21.7.1987; USA-prior. 30.5.1986).
EP 409 281 (Warner-Lambert; appl. 23.1.1991; USA-prior. 21.7.1989, 26.2.1991).
EP 680 320 ( Warner-Lambert; appl. 8.11.1995; USA-prior. 19.1.1993).
c Naeminga, T. et al.: Tetrahedron Lett. (TELEAY) 33, 2279-2282 (1992).
WO 9 703 960 (Warner-Lambert; appl. 6.2.1997; USA-prior. 17.7.1995).
ca Baumann, K.L. et al.: Tetrahedron Lett. (TELEAY) 33, 2283-2284 (1992).
cb Isbell, H. et al.: Carbohydr. Res. (CRBRAT) 72, 301-304 (1972).
d Roth, B.D. et al.: J. Med. Chem. (JMCMAR) 34, 357-366 (1991).

tags-synthesis of drugs,method of preparation of Atorvastatin calcium,molecular weight Atorvastatin calcium , molecular formula of  Atorvastatin calcium