Sunday 29 April 2012

Laboratory Synthesis Of Clofibrate

CLOFIBRATE SYNTHESIS



References
1.      Jones et al., GB 860303 (1961 to I.C.I.).
2.      Prepn: Galimberti, Defranceschi, Gazz. Chim. Ital. 77, 431 (1947);
3.      Gilman, Wilder, J. Am. Chem. Soc. 77, 6644 (1955);
4.      Prepn and resolution of isomers: Witiak et al., J. Med. Chem. 11, 1086
5.      US patent 4739101
6.      US patent 3262850

3 comments:

  1. How you do this synthesis in the lab?

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  2. The first step is à la the Reimer–Tiemann reaction.

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  3. its better if u mention the starting materials name ,..

    ReplyDelete