Monday 28 November 2011

Laboratory Synthesis Of Allantoin

CHEMICAL NAME IUPAC : chloro [(2 ,5- di oxo- 4- imidazolidinyl )uretato ]tetra hydroxy aluminum
Allantoin Use: wound remedy, antipsoriatic, adstringent, webstimulant, keratolytic, antacid
Allantoin MW: 158.12
Allantoin MF: C4H6N4O3

Alcloxa Allantoin
RN: 1317-25-5 EINECS: 215-262-3
MW: 314.55
MF: C4H9Al2ClN4O7
LD50: >8 g/kg (M,R, p.o.)
CN: chloro [(2 ,5- di oxo- 4- imidazolidinyl )uretato ]tetra hydroxy aluminum
Aldioxa Allantoin
RN: 5579-81-7 EINECS: 226-964-4
MW: 218.11
MF: C4H7AlN4O5
LD50: >8 g/kg (M, p.o.)
CN: [(2 ,5- di oxo- 4- imidazolidinyl )ureato ]di hydroxy aluminum
Reference(s):
  1. DOS 1 939 924 (BASF; appl. 6.8.1969).
  2. from glyoxal via "in situ"-glyoxylic acid:DOS 2 714 938 (Akad. d. Wiss. der DDR; appl. 2.4.1977; DDR-prior. 29.10.1976).
  3. from chloral hydrate via "in situ"-glyoxylic acid:DOS 2 717 698 (Akad. d. Wiss. der DDR; appl. 21.4.1977; DDR-prior. 29.10.1976).
  4. by oxidation of uric acid with PbO, or H2O2 or potassium permanganate:Org. Synth. (ORSYAT) 13 1 (1933).
  5. by oxidation of glycoluril with H2O2:Biltz, H.; Schiemann, G.: J. Prakt. Chem. (JPCEAO) 113, 92 (1926).US 2 802 011 (Carbogen Corp.; 1957; appl. 1956).
  6. by condensation of glyoxylic acid esters or glyoxylic acid acetal esters with urea:US 2 158 098 (Merck & Co.; 1939; appl. 1937).
tags-synthesis of drugs,method of preparation of Allantoin,molecular weight Allantoin , molecular formula of Allantoin  

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