Saturday, 13 October 2012

Laboratory Synthesis Of Fenbufen

Fenbufen Synthesis

SYNTHESIS

Tomeufeik, A.; et al. (American Cyanamid Co.); Compositions containing substituted benzoylpropionic acids and method of use to treat inflammation and pain. 

REFERENCE 

  1. Fenbufen. Drugs Fut 1976, 1, 1, 21

  2. DE 2147111; FR 2107848; GB 1320076; US 3784701 

    MW: 254.29 MF: C16H14O3
    LD50 Fenbufen : 795 mg/kg (M, p.o.);200 mg/kg (R, p.o.)

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