Laboratory Synthesis Of Fenbufen

Fenbufen Synthesis

SYNTHESIS

Tomeufeik, A.; et al. (American Cyanamid Co.); Compositions containing substituted benzoylpropionic acids and method of use to treat inflammation and pain. 

REFERENCE 

1. Fenbufen. Drugs Fut 1976, 1, 1, 21

2. DE 2147111; FR 2107848; GB 1320076; US 3784701 

   MW: 254.29 MF: C16H14O3
   LD50 Fenbufen : 795 mg/kg (M, p.o.);200 mg/kg (R, p.o.)